Clinical Medicine & Physiology
Fujimoto (1968) & Kurazumi (1994) Body Surface Area (BSA) Formula: Precision Drug & GFR Indexing
Calculate Body Surface Area (m^2) using Shigeki Fujimoto et al.’s (1968) Japanese/East Asian clinical standard BSA = 0.008883 * H^0.663 * W^0.444 and Yutaka Kurazumi et al.’s (1994) modern 3D-validated reference BSA = 0.00949 * H^0.655 * W^0.441.
Why PMDA oncology trials and JSN nephrology eGFR indexing specify Fujimoto BSA over DuBois!
DuBois & DuBois (1916, 0.007184 * H^0.725 * W^0.425) was derived on just 9 North American subjects in 1916 and systematically overpredicts East Asian body surface area by ~2.5%–3.5% due to trunk-to-limb proportion differences! Directly paper-coating and planimetering 201 infants, children, and adults across all ages, Shigeki Fujimoto, T. Watanabe et al. (1968, Japanese Journal of Hygiene) established the official Japanese clinical pharmacology and Japanese Society of Nephrology (JSN) BSA standard:
BSA_Fujimoto (m^2) = 0.008883 * (Height_cm^0.663) * (Weight_kg^0.444)! Expanding direct surface measurements to 259 healthy contemporary young and older adults in thermal-comfort and ergonomics research, Yutaka Kurazumi et al. (1994, Japanese Journal of Biometeorology) refined the modern adult reference equation: BSA_Kurazumi (m^2) = 0.00949 * (Height_cm^0.655) * (Weight_kg^0.441) (~3.2% higher than Fujimoto, closely tracking DuBois/Mosteller in modern cohorts)!
| Patient Anthropometry | Fujimoto (1968) BSA (m^2) | Kurazumi (1994) BSA (m^2) | DuBois (1916) Reference |
|---|---|---|---|
| Older Female (152 cm, 48 kg) | 1.3855 m^2 | 1.4067 m^2 | 1.4258 m^2 |
| Standard Adult (170 cm, 63 kg) | 1.6837 m^2 | 1.7050 m^2 | 1.7302 m^2 |
| Larger Adult (180 cm, 82 kg) | 1.9701 m^2 | 1.9922 m^2 | 2.0185 m^2 |
Fujimoto et al. (1968) Body Surface Area BSA (m^2)
Evaluates 0.008883 * (Height_cm^0.663) * (Weight_kg^0.444) across Height B2 (cm) and Weight B3 (kg).
=IF(OR(B2 < 40, B2 > 230, B3 < 2, B3 > 250), "Invalid Height (cm) or Weight (kg)", ROUND(0.008883 * (B2 ^ 0.663) * (B3 ^ 0.444), 4))Kurazumi et al. (1994) Modern Adult Body Surface Area BSA (m^2)
Evaluates 0.00949 * (Height_cm^0.655) * (Weight_kg^0.441) for thermal physiology and comparative pharmacometrics.
=IF(OR(B2 < 40, B2 > 230, B3 < 2, B3 > 250), "Invalid Height (cm) or Weight (kg)", ROUND(0.00949 * (B2 ^ 0.655) * (B3 ^ 0.441), 4))Try the example
Use the original values or change them to test your understanding.